The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression. [electronic resource]
Producer: 20120413Description: 1033-42 p. digitalISSN:- 1098-2264
- Apoptosis -- drug effects
- Azacitidine -- analogs & derivatives
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Decitabine
- Depsipeptides -- pharmacology
- Down-Regulation -- drug effects
- Drug Resistance, Neoplasm
- Endoderm -- drug effects
- Gene Knockdown Techniques -- methods
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- metabolism
- Homeodomain Proteins -- biosynthesis
- Humans
- Male
- Nanog Homeobox Protein
- Octamer Transcription Factor-3 -- genetics
- SOXF Transcription Factors -- genetics
- Seminoma -- drug therapy
- Testicular Neoplasms -- drug therapy
- Transcription Factor AP-2 -- genetics
- Tranylcypromine -- pharmacology
- Tretinoin -- pharmacology
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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