YHHU0895, a novel synthetic small-molecule microtubule-destabilizing agent, effectively overcomes P-glycoprotein-mediated tumor multidrug resistance. [electronic resource]
Producer: 20120118Description: 54-62 p. digitalISSN:- 1872-7980
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- physiology
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Drug Resistance, Multiple
- Drug Resistance, Neoplasm
- Female
- Humans
- Indoles -- pharmacology
- Mice
- Microtubules -- drug effects
- Polymerization
- Pyrimidines -- pharmacology
- Tubulin -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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