Death receptor pathway activation and increase of ROS production by the triple epigenetic inhibitor UVI5008. [electronic resource]
Producer: 20120511Description: 2394-404 p. digitalISSN:- 1538-8514
- Animals
- Antineoplastic Agents -- pharmacology
- Cells, Cultured
- Disulfides -- pharmacology
- Down-Regulation -- drug effects
- Epigenesis, Genetic -- drug effects
- Female
- HCT116 Cells
- HL-60 Cells
- Humans
- K562 Cells
- Mice
- Mice, Nude
- Oximes -- pharmacology
- Reactive Oxygen Species -- metabolism
- Receptors, Death Domain -- agonists
- Signal Transduction -- drug effects
- U937 Cells
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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