Down-regulated HS6ST2 in osteoarthritis and Kashin-Beck disease inhibits cell viability and influences expression of the genes relevant to aggrecan metabolism of human chondrocytes. [electronic resource]
Producer: 20120112Description: 2176-86 p. digitalISSN:- 1462-0332
- ADAM Proteins -- metabolism
- Adult
- Aged
- Aggrecans -- metabolism
- Analysis of Variance
- Cartilage, Articular -- metabolism
- Cell Line
- Cell Survival -- physiology
- Chondrocytes -- metabolism
- DNA, Complementary -- metabolism
- Down-Regulation
- Female
- Gene Expression
- Humans
- Kashin-Beck Disease -- genetics
- Male
- Matrix Metalloproteinase 3 -- metabolism
- Middle Aged
- Osteoarthritis -- genetics
- Phenotype
- RNA, Messenger -- metabolism
- RNA, Small Interfering -- pharmacology
- SOX9 Transcription Factor -- metabolism
- Sulfotransferases -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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