Nitisinone improves eye and skin pigmentation defects in a mouse model of oculocutaneous albinism. [electronic resource]
Producer: 20111121Description: 3914-23 p. digitalISSN:- 1558-8238
- Albinism, Oculocutaneous -- drug therapy
- Animals
- Cyclohexanones -- therapeutic use
- Disease Models, Animal
- Enzyme Inhibitors -- therapeutic use
- Enzyme Stability -- drug effects
- Eye Color -- drug effects
- Female
- Humans
- Melanins -- metabolism
- Melanocytes -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Microscopy, Electron, Transmission
- Models, Molecular
- Monophenol Monooxygenase -- chemistry
- Mutation
- Nitrobenzoates -- therapeutic use
- Pregnancy
- Skin Pigmentation -- drug effects
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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