Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells. [electronic resource]
Producer: 20120109Description: 64-75 p. digitalISSN:- 1872-7980
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Brain -- metabolism
- CDC2 Protein Kinase
- Carbanilides -- pharmacology
- Cell Cycle Checkpoints -- genetics
- Cell Division -- genetics
- Cell Line, Tumor
- Checkpoint Kinase 2
- Cyclin B -- genetics
- Cyclin B1 -- genetics
- Cyclin-Dependent Kinases
- G2 Phase -- genetics
- Humans
- Meningioma -- genetics
- Mice
- Mice, Nude
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA Interference
- Receptors, Urokinase Plasminogen Activator -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Burden
- Xenograft Model Antitumor Assays -- methods
- cdc25 Phosphatases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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