Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-α. [electronic resource]
Producer: 20120313Description: 229-42 p. digitalISSN:- 1097-4547
- Animals
- Apoptosis -- drug effects
- Cell Membrane -- drug effects
- Ceramides
- Cerebral Cortex -- cytology
- Chick Embryo
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Growth Cones -- drug effects
- Humans
- Magnesium -- metabolism
- NADPH Oxidases -- metabolism
- Neurites -- drug effects
- Neuroblastoma -- pathology
- Neurons -- cytology
- Palmitates -- pharmacology
- Phosphotransferases (Alcohol Group Acceptor) -- metabolism
- RNA, Small Interfering -- pharmacology
- Reactive Oxygen Species
- Sphingomyelin Phosphodiesterase -- metabolism
- Tumor Necrosis Factor-alpha -- toxicity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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