Hydroxyurea decreases gemcitabine resistance in pancreatic carcinoma cells with highly expressed ribonucleotide reductase. [electronic resource]
Producer: 20120522Description: 107-13 p. digitalISSN:- 1536-4828
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- genetics
- Antigens, CD
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- Cadherins -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Deoxycytidine -- analogs & derivatives
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Homeodomain Proteins -- genetics
- Humans
- Hydroxyurea -- pharmacology
- Multidrug Resistance-Associated Proteins -- genetics
- Neoplasm Proteins -- genetics
- Pancreatic Neoplasms -- enzymology
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- Ribonucleotide Reductases -- antagonists & inhibitors
- Snail Family Transcription Factors
- Transcription Factors -- genetics
- Vimentin -- genetics
- Zinc Finger E-box-Binding Homeobox 1
- Gemcitabine
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Publication Type: Journal Article
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