Insulin-like growth factor-1 preconditioning accentuates intrinsic survival mechanism in stem cells to resist ischemic injury by orchestrating protein kinase cα-erk1/2 activation. [electronic resource]
Producer: 20120514Description: 217-27 p. digitalISSN:- 1557-7716
- Animals
- Antigens, Ly -- metabolism
- Calcium -- metabolism
- Cell Hypoxia
- Cell Survival
- Cells, Cultured
- Cytoprotection
- Enzyme Activation
- Female
- Glucose -- deficiency
- Insulin-Like Growth Factor I -- pharmacology
- Male
- Membrane Proteins -- metabolism
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Myocardial Infarction -- pathology
- Myocardial Ischemia -- pathology
- Myocardium -- metabolism
- Protein Kinase C-alpha -- metabolism
- Rats
- Rats, Inbred F344
- Stem Cell Transplantation
- Stem Cells -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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