The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU. [electronic resource]
Producer: 20120215Description: 1285-94 p. digitalISSN:- 1573-675X
- 14-3-3 Proteins -- genetics
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- genetics
- Biomarkers, Tumor -- genetics
- Cell Line, Tumor
- Colonic Neoplasms -- drug therapy
- Exonucleases -- genetics
- Exoribonucleases
- Fluorouracil -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Protein Binding -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- genetics
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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