Oncogenic ras-induced down-regulation of pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells. [electronic resource]
Producer: 20111227Description: 38894-903 p. digitalISSN:- 1083-351X
- Animals
- Anoikis -- genetics
- Caspase 2 -- biosynthesis
- Cell Line, Tumor
- Cell Transformation, Neoplastic -- genetics
- Cysteine Endopeptidases -- biosynthesis
- Cytochromes c -- genetics
- Cytoplasm -- genetics
- Down-Regulation
- Epithelial Cells -- metabolism
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Neoplastic
- High-Temperature Requirement A Serine Peptidase 2
- Humans
- Intestinal Mucosa -- metabolism
- MAP Kinase Kinase Kinases -- genetics
- Mice
- Mitochondrial Proteins -- genetics
- Neoplasm Proteins -- genetics
- Rats
- Serine Endopeptidases -- genetics
- Signal Transduction -- genetics
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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