Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins. [electronic resource]
Producer: 20120203Description: 669-80 p. digitalISSN:- 1096-0007
- Animals
- Apoptosis
- Blotting, Western
- Cell Cycle Proteins
- Cell Differentiation
- Cell Survival
- Cells, Cultured
- Ciliary Neurotrophic Factor -- metabolism
- DNA Primers -- chemistry
- Eye Proteins -- physiology
- Fluorescent Antibody Technique, Indirect
- Golgi Apparatus -- metabolism
- Membrane Transport Proteins
- Mice
- Nerve Growth Factors -- metabolism
- Neurotrophin 3 -- metabolism
- RNA Interference
- RNA, Small Interfering -- genetics
- Real-Time Polymerase Chain Reaction
- Retinal Ganglion Cells -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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