Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues. [electronic resource]
Producer: 20120402Description: 996-1010 p. digitalISSN:- 1474-9726
- Adipose Tissue, Brown -- metabolism
- Adipose Tissue, White -- metabolism
- Adiposity -- genetics
- Aging -- genetics
- Animals
- Diabetes Mellitus, Type 2 -- complications
- Eating -- physiology
- Energy Metabolism -- physiology
- Gene Expression Regulation
- Ghrelin -- genetics
- Humans
- Insulin Resistance -- genetics
- Ion Channels -- genetics
- Lipid Metabolism -- genetics
- Male
- Mice
- Mice, Knockout
- Mitochondrial Proteins -- genetics
- Obesity -- complications
- Receptors, Ghrelin -- antagonists & inhibitors
- Signal Transduction -- genetics
- Thermogenesis -- physiology
- Uncoupling Protein 1
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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