Targeted systemic radiotherapy with scVEGF/177Lu leads to sustained disruption of the tumor vasculature and intratumoral apoptosis. [electronic resource]
Producer: 20111129Description: 1630-7 p. digitalISSN:- 1535-5667
- Angiogenesis Inhibitors -- therapeutic use
- Animals
- Antibodies, Monoclonal, Humanized -- therapeutic use
- Apoptosis -- radiation effects
- Bevacizumab
- Breast Neoplasms -- blood supply
- Cell Line, Tumor
- Cell Survival -- radiation effects
- Combined Modality Therapy
- Endothelial Cells -- radiation effects
- Female
- Humans
- Indoles -- therapeutic use
- Lutetium -- pharmacokinetics
- Mice
- Mice, Inbred BALB C
- Mice, Inbred ICR
- Mice, SCID
- Neovascularization, Pathologic -- radiotherapy
- Pyrroles -- therapeutic use
- Radioisotopes -- pharmacokinetics
- Radiopharmaceuticals -- pharmacokinetics
- Receptors, Vascular Endothelial Growth Factor -- antagonists & inhibitors
- Sunitinib
- Vascular Endothelial Growth Factor A -- pharmacokinetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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