Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics. [electronic resource]
Producer: 20120409Description: 2219-32 p. digitalISSN:- 1521-009X
- Administration, Oral
- Animals
- Benzimidazoles -- administration & dosage
- Biological Availability
- Caco-2 Cells
- Chromatography, Liquid
- Cytochrome P-450 Enzyme System -- metabolism
- Dogs
- Female
- Histone Deacetylase Inhibitors -- administration & dosage
- Humans
- Male
- Mice
- Mice, Inbred BALB C
- Microsomes, Liver -- enzymology
- Rats
- Rats, Wistar
- Tandem Mass Spectrometry
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Publication Type: Journal Article
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