Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease. [electronic resource]
Producer: 20111014Description: 567-79 p. digitalISSN:- 1540-8140
- CDC2 Protein Kinase -- metabolism
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Checkpoint Kinase 1
- Cyclin-Dependent Kinase 2 -- metabolism
- DNA Damage
- DNA Replication -- drug effects
- DNA-Binding Proteins -- genetics
- Endodeoxyribonucleases -- genetics
- Endonucleases -- genetics
- Flow Cytometry
- Genomic Instability
- HEK293 Cells
- High-Throughput Screening Assays
- Histones -- metabolism
- Humans
- Hydroxyurea -- pharmacology
- Microscopy, Fluorescence
- Mutation
- Nuclear Proteins -- genetics
- Nucleic Acid Synthesis Inhibitors -- pharmacology
- Phosphorylation
- Protein Kinases -- metabolism
- Protein-Tyrosine Kinases -- genetics
- RNA Interference
- S Phase
- Time Factors
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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