Incorporation of immunostimulatory motifs in the transcribed region of a plasmid DNA vaccine enhances Th1 immune responses and therapeutic effect against Mycobacterium tuberculosis in mice. [electronic resource]
Producer: 20120123Description: 7624-30 p. digitalISSN:- 1873-2518
- Amino Acid Motifs -- genetics
- Animals
- Antibodies, Bacterial -- blood
- B7-1 Antigen -- biosynthesis
- B7-2 Antigen -- biosynthesis
- Bacterial Load
- Bacterial Proteins -- genetics
- Cell Line
- Chaperonin 60 -- genetics
- Cytokines -- biosynthesis
- Gene Expression
- Gene Expression Profiling
- Immunoglobulin G -- blood
- Immunologic Factors -- genetics
- Lung -- microbiology
- Macrophages -- immunology
- Mice
- Mycobacterium leprae -- genetics
- Mycobacterium tuberculosis -- genetics
- Plasmids
- Spleen -- microbiology
- Th1 Cells -- immunology
- Tuberculosis -- immunology
- Tuberculosis Vaccines -- administration & dosage
- Vaccines, DNA -- administration & dosage
- Vaccines, Synthetic -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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