CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast. [electronic resource]
Producer: 20120501Description: 257-67 p. digitalISSN:- 1365-2125
- 14-alpha Demethylase Inhibitors -- pharmacology
- Acetates -- pharmacokinetics
- Adult
- Anti-Asthmatic Agents -- pharmacokinetics
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- physiology
- Cross-Over Studies
- Cyclopropanes
- Cytochrome P-450 CYP2C8
- Cytochrome P-450 CYP3A -- physiology
- Drug Interactions
- Female
- Gemfibrozil -- pharmacology
- Humans
- Hypolipidemic Agents -- pharmacology
- Itraconazole -- pharmacology
- Male
- Quinolines -- pharmacokinetics
- Sulfides
- Young Adult
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Publication Type: Clinical Trial, Phase IV; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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