Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. [electronic resource]
Producer: 20120502Description: 2085-92 p. digitalISSN:- 1521-009X
- Cryopreservation
- Cytochrome P-450 CYP3A -- metabolism
- Cytochrome P-450 CYP3A Inhibitors
- Diltiazem -- pharmacology
- Drug Interactions
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Erythromycin -- pharmacology
- Hepatocytes -- drug effects
- Humans
- Microsomes, Liver -- drug effects
- Pharmacokinetics
- Risk Assessment -- methods
- Time Factors
- Troleandomycin -- pharmacology
- Verapamil -- pharmacology
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Publication Type: Journal Article
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