Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases signaling pathway. [electronic resource]
Producer: 20120116Description: 403-11 p. digitalISSN:- 1521-0103
- Anacardic Acids -- pharmacology
- Angiogenesis Inhibitors -- pharmacology
- Animals
- Cell Proliferation -- drug effects
- Chick Embryo
- Chorioallantoic Membrane -- drug effects
- Corneal Neovascularization -- drug therapy
- Dose-Response Relationship, Drug
- Focal Adhesion Kinase 1 -- metabolism
- GTP Phosphohydrolases -- metabolism
- Human Umbilical Vein Endothelial Cells
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Molecular Targeted Therapy
- Neovascularization, Pathologic -- drug therapy
- Prostatic Neoplasms -- blood supply
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Time Factors
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
- rho GTP-Binding Proteins -- agonists
- rho-Associated Kinases -- metabolism
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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