Corydaline inhibits multiple cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes. [electronic resource]
Producer: 20111118Description: 6591-602 p. digitalISSN:- 1420-3049
- Analgesics -- chemistry
- Anti-Allergic Agents -- chemistry
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Berberine Alkaloids -- chemistry
- Chemistry, Pharmaceutical
- Chromatography, Liquid
- Corydalis -- chemistry
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP2C9
- Cytochrome P-450 CYP3A -- metabolism
- Cytochrome P-450 CYP3A Inhibitors
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- chemistry
- Glucuronosyltransferase -- antagonists & inhibitors
- Humans
- Hydroxylation
- Kinetics
- Liver -- drug effects
- Microsomes, Liver -- drug effects
- Tandem Mass Spectrometry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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