Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor. [electronic resource]
Producer: 20111109Description: 6206-14 p. digitalISSN:- 1520-4804
- Adenosine Triphosphate -- chemistry
- Amino Acid Motifs
- Animals
- Binding, Competitive
- Cell Line
- Chemical and Drug Induced Liver Injury -- prevention & control
- Consensus Sequence
- Cytokines -- metabolism
- Diabetes Mellitus, Type 2 -- drug therapy
- Drug Design
- Female
- Glucose Intolerance -- drug therapy
- Humans
- Hypoglycemic Agents -- chemical synthesis
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Models, Molecular
- Molecular Mimicry
- Peptides -- chemical synthesis
- Phosphorylation
- Protein Binding
- Structure-Activity Relationship
- Substrate Specificity
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.