Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10. [electronic resource]
Producer: 20120110Description: 793-802 p. digitalISSN:- 1573-7276
- ADAM Proteins -- antagonists & inhibitors
- ADAM10 Protein
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Animals
- Blotting, Western
- Cell Proliferation
- Cells, Cultured
- Gene Expression Regulation, Neoplastic
- Hepatocyte Growth Factor -- pharmacology
- Humans
- Kidney -- cytology
- Liver Neoplasms, Experimental -- genetics
- Membrane Proteins -- antagonists & inhibitors
- Mice
- Mice, Inbred DBA
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-met -- antagonists & inhibitors
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Survival Rate
- Tissue Inhibitor of Metalloproteinase-1 -- antagonists & inhibitors
- Tumor Microenvironment
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Publication Type: Journal Article
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