Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice. [electronic resource]
Producer: 20120216Description: 90-5 p. digitalISSN:- 1878-5883
- Acetylcholinesterase -- genetics
- Alanine -- genetics
- Analysis of Variance
- Animals
- Brain-Derived Neurotrophic Factor -- metabolism
- Cerebral Cortex -- drug effects
- Choline O-Acetyltransferase -- metabolism
- Cholinergic Fibers -- pathology
- Disease Models, Animal
- Dopamine -- deficiency
- Gene Expression Regulation -- drug effects
- MPTP Poisoning -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation -- genetics
- Neurons -- enzymology
- Proline -- genetics
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2
- Receptor, trkB -- metabolism
- Time Factors
- alpha-Synuclein -- genetics
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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