Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. [electronic resource]
Producer: 20120312Description: 629-40 p. digitalISSN:- 1420-9071
- Anaphase
- Apoptosis
- Cell Line
- DNA End-Joining Repair
- DNA-Activated Protein Kinase -- antagonists & inhibitors
- G-Quadruplexes
- Homologous Recombination
- Humans
- Ligands
- Metaphase
- Mitosis -- genetics
- Nuclear Proteins -- antagonists & inhibitors
- Pyridines -- pharmacology
- Quinolines -- pharmacology
- RNA Interference
- RNA, Small Interfering -- metabolism
- Rad51 Recombinase -- antagonists & inhibitors
- Telomere -- metabolism
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Publication Type: Journal Article
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