Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans. [electronic resource]
Producer: 20111121Description: 3003-12 p. digitalISSN:- 1528-0020
- Adult
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized -- pharmacology
- Antineoplastic Agents, Alkylating -- therapeutic use
- Brain Neoplasms -- immunology
- Cancer Vaccines -- therapeutic use
- Cells, Cultured
- Combined Modality Therapy
- Dacarbazine -- analogs & derivatives
- Daclizumab
- Drug Evaluation, Preclinical
- Glioblastoma -- immunology
- Humans
- Immunoglobulin G -- pharmacology
- Immunotherapy -- methods
- Interleukin-2 Receptor alpha Subunit -- antagonists & inhibitors
- Lymphocyte Depletion -- methods
- Lymphopenia -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Middle Aged
- Substrate Specificity -- drug effects
- T-Lymphocytes, Regulatory -- cytology
- Temozolomide
- Young Adult
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
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