Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. [electronic resource]
Producer: 20111003Description: 360-4 p. digitalISSN:- 1524-4571
- Cardiac Myosins -- genetics
- Cell Differentiation -- drug effects
- Cell Line
- Dose-Response Relationship, Drug
- Drug Discovery
- Embryonic Stem Cells -- drug effects
- Gene Expression Profiling
- Gene Expression Regulation, Developmental -- drug effects
- Genes, Reporter
- High-Throughput Screening Assays
- Humans
- Luminescent Proteins -- biosynthesis
- Mesoderm -- cytology
- Microscopy, Fluorescence
- Myocytes, Cardiac -- drug effects
- Myosin Heavy Chains -- genetics
- Promoter Regions, Genetic -- drug effects
- Signal Transduction -- drug effects
- Small Molecule Libraries
- Time Factors
- Transfection
- Wnt Proteins -- antagonists & inhibitors
- Red Fluorescent Protein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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