Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase. [electronic resource]
Producer: 20111102Description: e21525 p. digitalISSN:- 1932-6203
- Catalytic Domain
- Fluorescence Resonance Energy Transfer
- Fluorescent Dyes -- metabolism
- Heparin -- pharmacology
- Humans
- Hydrogen-Ion Concentration -- drug effects
- Hydrolysis -- drug effects
- Kinetics
- Leukocyte Elastase -- metabolism
- Models, Molecular
- Peptides -- metabolism
- Protein Processing, Post-Translational -- drug effects
- Substrate Specificity -- drug effects
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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