Notch gain of function in mouse periocular mesenchyme downregulates FoxL2 and impairs eyelid levator muscle formation, leading to congenital blepharophimosis. [electronic resource]
Producer: 20111214Description: 2561-72 p. digitalISSN:- 1477-9137
- Actins -- genetics
- Animals
- Apoptosis -- genetics
- Blepharophimosis -- genetics
- Blotting, Western
- Cell Proliferation
- Chromatin Immunoprecipitation
- Eyelids -- metabolism
- Forkhead Box Protein L2
- Forkhead Transcription Factors -- genetics
- Immunohistochemistry
- Mice
- Mice, Transgenic
- Muscle, Smooth -- metabolism
- NIH 3T3 Cells
- Receptor, Notch1 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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