Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer? [electronic resource]
Producer: 20120320Description: 325-32 p. digitalISSN:- 1938-0674
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal -- therapeutic use
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents -- therapeutic use
- Biomarkers, Tumor -- genetics
- Cetuximab
- Colorectal Neoplasms -- drug therapy
- DNA, Neoplasm -- genetics
- Drug Resistance, Neoplasm
- ErbB Receptors -- antagonists & inhibitors
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Immunoenzyme Techniques
- Male
- Middle Aged
- Mutation -- genetics
- Neoplasm Metastasis
- PTEN Phosphohydrolase -- genetics
- Polymerase Chain Reaction
- Prognosis
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins c-met -- metabolism
- Proto-Oncogene Proteins p21(ras)
- Receptor, IGF Type 1 -- metabolism
- Retrospective Studies
- Survival Rate
- ras Proteins -- genetics
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Publication Type: Journal Article
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