Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite. [electronic resource]
Producer: 20111021Description: 113-20 p. digitalISSN:- 1879-3169
- Animals
- Anticarcinogenic Agents -- pharmacology
- Arsenites -- administration & dosage
- Carcinogens, Environmental -- administration & dosage
- Cell Line
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic -- chemically induced
- Cyclin D1 -- antagonists & inhibitors
- Fibroblasts -- drug effects
- G1 Phase -- drug effects
- Humans
- Lung -- drug effects
- Lung Neoplasms -- chemically induced
- Mice
- Mice, Nude
- Mitogen-Activated Protein Kinase 8 -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-jun -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering
- Signal Transduction -- drug effects
- Sodium Compounds -- administration & dosage
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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