Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. [electronic resource]
Producer: 20111230Description: 1727-37 p. digitalISSN:- 1873-3913
- Acetylcysteine -- analogs & derivatives
- Animals
- Blotting, Western
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Erythromycin -- analogs & derivatives
- Gene Expression Regulation -- physiology
- Glial Cell Line-Derived Neurotrophic Factor Receptors -- genetics
- Humans
- MAP Kinase Signaling System -- physiology
- Mitogen-Activated Protein Kinase 3 -- genetics
- Nerve Regeneration
- Neurites -- physiology
- Neurturin -- metabolism
- Phosphorylation -- drug effects
- Protein Isoforms -- genetics
- Proto-Oncogene Proteins c-ret -- genetics
- Rats
- Real-Time Polymerase Chain Reaction
- Signal Transduction -- physiology
- Transfection
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Publication Type: Journal Article
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