Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. [electronic resource]
Producer: 20110902Description: 1181-96 p. digitalISSN:- 1540-8140
- Animals
- Drosophila -- genetics
- Drosophila Proteins -- genetics
- GTP-Binding Proteins -- genetics
- Gene Expression Regulation, Developmental
- Heart -- physiology
- Heart Diseases -- genetics
- Homeobox Protein Nkx-2.5
- Homeodomain Proteins -- genetics
- Humans
- Mice
- MicroRNAs -- physiology
- Myocardial Contraction -- genetics
- Myocardium -- metabolism
- Myocytes, Cardiac -- cytology
- Repressor Proteins -- genetics
- Trans-Activators -- genetics
- Transcription Factors -- genetics
- cdc42 GTP-Binding Protein -- genetics
- rho GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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