EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin. [electronic resource]
Producer: 20120327Description: 583-94 p. digitalISSN:- 1476-5594
- Adult
- Animals
- Base Sequence
- Cadherins -- genetics
- Cell Line, Tumor
- DNA-Binding Proteins -- genetics
- Enhancer of Zeste Homolog 2 Protein
- Female
- Gene Expression Regulation, Neoplastic
- Histone Deacetylase 1 -- genetics
- Histone Deacetylase 2 -- genetics
- Humans
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Molecular Sequence Data
- Multiprotein Complexes -- metabolism
- Nasopharyngeal Neoplasms -- genetics
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Polycomb Repressive Complex 2
- Promoter Regions, Genetic -- genetics
- Protein Binding
- RNA Interference
- Repressor Proteins -- metabolism
- Snail Family Transcription Factors
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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