PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. [electronic resource]
Producer: 20120330Description: 1132-44 p. digitalISSN:- 1554-8635
- Adenine -- analogs & derivatives
- Animals
- Apoptosis
- Autophagy
- Gene Expression Regulation, Neoplastic
- Humans
- Leukemia, Promyelocytic, Acute -- metabolism
- Mice
- Microtubule-Associated Proteins -- metabolism
- Neoplasm Transplantation
- Oncogene Proteins, Fusion -- metabolism
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Recombinant Fusion Proteins -- chemistry
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Time Factors
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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