Propofol post-conditioning protects against cardiomyocyte apoptosis in hypoxia/reoxygenation injury by suppressing nuclear factor-kappa B translocation via extracellular signal-regulated kinase mitogen-activated protein kinase pathway. [electronic resource]
Producer: 20110930Description: 525-34 p. digitalISSN:- 1365-2346
- Active Transport, Cell Nucleus
- Analysis of Variance
- Anesthetics, Intravenous -- pharmacology
- Animals
- Animals, Newborn
- Apoptosis -- drug effects
- Blotting, Western
- Cell Survival -- drug effects
- Cells, Cultured
- Enzyme Activation
- Flow Cytometry
- Fluorescent Antibody Technique
- MAP Kinase Signaling System -- drug effects
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3 -- antagonists & inhibitors
- Myocardial Reperfusion Injury -- embryology
- Myocytes, Cardiac -- drug effects
- NF-kappa B -- metabolism
- Phosphorylation
- Propofol -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Rats
- Reactive Oxygen Species -- metabolism
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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