Gab2, via PI-3K, regulates ARF1 in FcεRI-mediated granule translocation and mast cell degranulation. [electronic resource]
Producer: 20110923Description: 932-41 p. digitalISSN:- 1550-6606
- ADP-Ribosylation Factor 1 -- deficiency
- Adaptor Proteins, Signal Transducing
- Anaphylaxis -- genetics
- Animals
- Binding Sites -- genetics
- Bone Marrow Cells -- enzymology
- Cell Degranulation -- genetics
- Cell Line
- Cell Membrane -- enzymology
- Cells, Cultured
- Cytoplasmic Granules -- enzymology
- Down-Regulation -- genetics
- Gene Knock-In Techniques
- Mast Cells -- enzymology
- Mice
- Mice, 129 Strain
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoproteins -- biosynthesis
- Protein Transport -- immunology
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- metabolism
- Receptors, IgE -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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