MDM2 promoter SNP309 is associated with an increased susceptibility to chronic lymphocytic leukemia and correlates with MDM2 mRNA expression in Chinese patients with CLL. [electronic resource]
Producer: 20120515Description: 2054-61 p. digitalISSN:- 1097-0215
- Adult
- Aged
- Aged, 80 and over
- Chromosome Aberrations
- Disease-Free Survival
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Heterozygote
- Humans
- Kaplan-Meier Estimate
- Leukemia, Lymphocytic, Chronic, B-Cell -- genetics
- Male
- Middle Aged
- Polymorphism, Single Nucleotide -- genetics
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-mdm2 -- genetics
- RNA, Messenger -- genetics
- Risk Factors
- Sequence Deletion
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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