Anaplastic lymphoma kinase (ALK) inhibitor response in neuroblastoma is highly correlated with ALK mutation status, ALK mRNA and protein levels. [electronic resource]
Producer: 20120503Description: 409-17 p. digitalISSN:- 2211-3436
- Anaplastic Lymphoma Kinase
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Gene Dosage
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Mutation -- genetics
- Neuroblastoma -- drug therapy
- Neurons -- drug effects
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Pyrimidines -- pharmacology
- RNA, Messenger -- genetics
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Schwann Cells -- drug effects
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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