A novel synthetic mono-carbonyl analogue of curcumin, A13, exhibits anti-inflammatory effects in vivo by inhibition of inflammatory mediators. [electronic resource]
Producer: 20120828Description: 594-604 p. digitalISSN:- 1573-2576
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Capillary Permeability -- drug effects
- Cells, Cultured
- Curcumin -- analogs & derivatives
- Cyclopentanes -- chemical synthesis
- Inflammation -- drug therapy
- Inflammation Mediators -- antagonists & inhibitors
- Interleukin-6 -- blood
- Lipopolysaccharides -- immunology
- Liver -- drug effects
- Lung -- drug effects
- Macrophage Activation
- Macrophages -- metabolism
- Macrophages, Peritoneal -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred ICR
- Nitric Oxide -- blood
- Pneumonia -- drug therapy
- Transcription, Genetic -- drug effects
- Tumor Necrosis Factor-alpha -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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