The Ras signaling pathway mediates cetuximab resistance in nasopharyngeal carcinoma. [electronic resource]
Producer: 20111205Description: 168-74 p. digitalISSN:- 1950-6007
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma
- Cell Line, Tumor
- Cetuximab
- Drug Resistance, Neoplasm
- Humans
- JNK Mitogen-Activated Protein Kinases -- biosynthesis
- Mitogen-Activated Protein Kinase 1 -- biosynthesis
- Mitogen-Activated Protein Kinase 3 -- biosynthesis
- NF-kappa B -- biosynthesis
- Nasopharyngeal Carcinoma
- Nasopharyngeal Neoplasms -- drug therapy
- Nucleoproteins -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Proto-Oncogene Proteins c-fos -- biosynthesis
- Proto-Oncogene Proteins p21(ras) -- genetics
- RNA, Small Interfering -- administration & dosage
- Signal Transduction -- drug effects
- Transfection
- p38 Mitogen-Activated Protein Kinases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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