Eicosapentaenoic acid ablates valproate-induced liver oxidative stress and cellular derangement without altering its clearance rate: dynamic synergy and therapeutic utility. [electronic resource]
Producer: 20110830Description: 460-7 p. digitalISSN:- 0006-3002
- Alanine Transaminase -- blood
- Alkaline Phosphatase -- blood
- Animals
- Anticonvulsants -- administration & dosage
- Drug Interactions
- Eicosapentaenoic Acid -- administration & dosage
- Glutathione -- metabolism
- Lipid Peroxidation -- drug effects
- Liver -- drug effects
- Male
- Metabolic Clearance Rate -- drug effects
- Mice
- Oxidative Stress -- drug effects
- Pentylenetetrazole -- toxicity
- Peroxidase -- metabolism
- Rats
- Rats, Sprague-Dawley
- Seizures -- chemically induced
- Tumor Necrosis Factor-alpha -- blood
- Valproic Acid -- administration & dosage
- gamma-Glutamyltransferase -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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