Aminopeptidase-N/CD13 is a potential proapoptotic target in human myeloid tumor cells. [electronic resource]
Producer: 20111014Description: 2831-42 p. digitalISSN:- 1530-6860
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal -- pharmacology
- Apoptosis -- drug effects
- CD13 Antigens -- antagonists & inhibitors
- Caspases -- metabolism
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- In Vitro Techniques
- Leukemia, Myeloid, Acute -- enzymology
- MAP Kinase Kinase 1 -- antagonists & inhibitors
- Male
- Membrane Potential, Mitochondrial
- Middle Aged
- Myeloid Cell Leukemia Sequence 1 Protein
- Phosphoinositide-3 Kinase Inhibitors
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerases -- metabolism
- Protease Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- U937 Cells
- Young Adult
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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