Inhibition of HSP90-dependent telomerase activity in amyloid β-induced apoptosis of cerebral endothelial cells. [electronic resource]
Producer: 20110726Description: 2041-51 p. digitalISSN:- 1097-4652
- Amyloid beta-Peptides -- toxicity
- Animals
- Apoptosis -- drug effects
- Benzoquinones -- pharmacology
- Caspase 3 -- metabolism
- Cells, Cultured
- Cerebrum -- drug effects
- Chromones -- pharmacology
- Cyclin-Dependent Kinase 4 -- metabolism
- Endothelium, Vascular -- drug effects
- HSP90 Heat-Shock Proteins -- metabolism
- Lactams, Macrocyclic -- pharmacology
- Macrolides -- pharmacology
- Membrane Potential, Mitochondrial
- Mice
- Morpholines -- pharmacology
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- RNA, Small Interfering -- metabolism
- Telomerase -- antagonists & inhibitors
- Tumor Suppressor Protein p53 -- metabolism
- Ubiquitination
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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