The synthesized novel fluorinated compound (LJJ-10) induces death receptor- and mitochondria-dependent apoptotic cell death in the human osteogenic sarcoma U-2 OS cells. [electronic resource]
Producer: 20150715Description: 2709-21 p. digitalISSN:- 1768-3254
- Acetylcysteine -- pharmacology
- Antibodies, Monoclonal -- pharmacology
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Apoptosis Inducing Factor -- genetics
- Apoptotic Protease-Activating Factor 1 -- genetics
- Caspases -- genetics
- Cell Line, Tumor
- Cyclosporine -- pharmacology
- Cytochromes c -- genetics
- DNA Fragmentation -- drug effects
- Fas Ligand Protein -- genetics
- Fas-Associated Death Domain Protein -- agonists
- Free Radical Scavengers -- pharmacology
- Gene Expression Regulation, Neoplastic
- Humans
- Mitochondria -- drug effects
- Osteoblasts -- drug effects
- Quinazolines -- chemical synthesis
- Reactive Oxygen Species -- agonists
- Signal Transduction
- fas Receptor -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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