Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice. [electronic resource]
Producer: 20120305Description: 1068-70 p. digitalISSN:- 1476-5578
- Amino Acid Substitution
- Animals
- Antidepressive Agents -- pharmacology
- Cerebral Cortex -- drug effects
- Depression -- drug therapy
- Disease Models, Animal
- Drug Evaluation, Preclinical
- Electroshock
- Gene Knock-In Techniques
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Helplessness, Learned
- Hippocampus -- drug effects
- Ketamine -- pharmacology
- Lithium Chloride -- pharmacology
- Mice
- Nerve Tissue Proteins -- antagonists & inhibitors
- Phosphorylation -- drug effects
- Phosphoserine -- metabolism
- Point Mutation
- Protein Processing, Post-Translational -- drug effects
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Publication Type: Letter
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