Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity. [electronic resource]
Producer: 20120525Description: R43 p. digitalISSN:- 1465-542X
- Antineoplastic Agents, Hormonal -- pharmacology
- Biomarkers, Tumor
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation
- Class I Phosphatidylinositol 3-Kinases
- Down-Regulation
- Drug Resistance, Neoplasm -- genetics
- Estrogen Receptor beta -- genetics
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Neuregulin-1 -- metabolism
- PTEN Phosphohydrolase -- genetics
- Phosphatidylinositol 3-Kinases -- genetics
- Proto-Oncogene Mas
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptor, ErbB-2 -- genetics
- Receptor, ErbB-3 -- genetics
- Signal Transduction
- Tamoxifen -- pharmacology
- Up-Regulation
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.