Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans. [electronic resource]
Producer: 20110809Description: 2093-103 p. digitalISSN:- 1469-7793
- Administration, Oral
- Adult
- Analysis of Variance
- Arginase -- antagonists & inhibitors
- Arginine -- metabolism
- Atorvastatin
- Biomarkers -- blood
- Biopsy
- Blood Flow Velocity
- Cholesterol -- blood
- Down-Regulation
- Enzyme Inhibitors -- administration & dosage
- Female
- Heptanoic Acids -- administration & dosage
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- administration & dosage
- Hypercholesterolemia -- blood
- Lipoproteins, LDL -- blood
- Male
- Microcirculation -- drug effects
- Microdialysis
- Middle Aged
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type III -- antagonists & inhibitors
- Pennsylvania
- Pyrroles -- administration & dosage
- Regional Blood Flow
- Skin -- blood supply
- Time Factors
- Treatment Outcome
- Triglycerides -- blood
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Publication Type: Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
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