Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate. [electronic resource]
Producer: 20110801Description: 4184-93 p. digitalISSN:- 1520-4995
- Animals
- Catalytic Domain -- genetics
- Deuterium Exchange Measurement
- Guanosine Monophosphate -- chemistry
- Humans
- Hydrogen-Ion Concentration
- Hypoxanthine Phosphoribosyltransferase -- chemistry
- Inosine Monophosphate -- chemistry
- Plasmodium falciparum -- enzymology
- Protein Binding -- genetics
- Purine Nucleotides -- chemistry
- Ribonucleotides -- chemistry
- Spectrum Analysis, Raman
- Substrate Specificity -- genetics
- Toxoplasma -- enzymology
- Xanthine
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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