Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice. [electronic resource]
Producer: 20110614Description: 1282-93 p. digitalISSN:- 1527-3350
- 1-Acylglycerophosphocholine O-Acyltransferase -- biosynthesis
- Animals
- Ceramides -- biosynthesis
- Cholestasis
- Female
- Homeostasis -- drug effects
- Lithocholic Acid -- blood
- Lysophosphatidylcholines -- blood
- Metabolome
- Mice
- Mice, Inbred C57BL
- Phospholipids -- metabolism
- RNA, Messenger -- metabolism
- Sphingolipids -- metabolism
- Sphingomyelin Phosphodiesterase -- biosynthesis
- Sphingomyelins -- blood
- Transforming Growth Factor beta -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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